Traditional Immunotherapy San Antonio

Dr. Amanda Trott-Gregorio

Traditional Immunotherapy
San Antonio

Stop Masking Allergies. Start Treating Them.

Juniper Allergy medical team
You’ve tried the antihistamines, the nasal sprays, the eye drops. They take the edge off for a few hours, then the sneezing, congestion, and itchy eyes come right back. Every season you brace yourself for the same misery, and every year you’re still only masking the symptoms, never touching the cause.

Traditional immunotherapy at Juniper Allergy in San Antonio takes a different approach. Instead of covering up your reactions, it gradually retrains your immune system to stop overreacting to the allergens that trigger you. Dr. Amanda Trott-Gregorio builds a treatment plan around your exact allergens, so you can move toward lasting relief instead of another year of temporary fixes.

Juniper Allergy medical team
Dr. Amanda Trott-Gregorio

Dr. Amanda Trott-Gregorio

Dr. Amanda Trott-Gregorio is a board-certified Allergist/Immunologist who has been in private practice in San Antonio for the past 10 years. Her personable demeanor and passion for resolving allergies has transformed the lives of countless patients.

A native of south Texas, Dr. Amanda Trott-Gregorio graduated from Texas A&M University in 2001. She received her MD from St. George’s University School of Medicine (2003-2007). She completed her residency training at UTMB in Galveston (2007-2010) and Allergy and Immunology fellowship training at Washington University in St. Louis (2010-2012).

Dr. Amanda Trott-Gregorio had the opportunity to learn from some of the most accomplished Allergists and Immunologists in the world at St. Louis Children’s Hospital and Barnes Jewish Hospital. Her research data has been published in peer-reviewed journals and she has written chapters in The Washington Manual and Nelson’s Textbook of Pediatrics. Dr. Amanda Trott-Gregorio is a fellow of the American College of Allergy, Asthma and Immunology.

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What Is Traditional Immunotherapy?

Healthcare professional administering a traditional immunotherapy allergy injection to an adult patient’s upper arm.

Traditional immunotherapy, commonly known as allergy shots, is a long-term treatment that gradually reduces your body’s sensitivity to specific allergens rather than simply masking your symptoms. By introducing small, carefully measured doses of your triggers through subcutaneous injections, it retrains your immune system to stop overreacting, addressing the root cause of your allergies instead of managing them season after season.

Treatment involves two phases. The first is the build-up phase, where you start at the lowest possible dose of your allergen and steadily increase over about six months until you reach your maintenance dose. Once that dose is reached, you enter the second phase, the maintenance phase, receiving the same dose once every two to four weeks to lock in long-term relief that can last for years after treatment ends.

 Healthcare professional administering a traditional immunotherapy allergy injection to an adult patient’s upper arm.
Comparison of traditional and cluster immunotherapy treatment schedules with allergy injections and calendar illustrations.

How Is Traditional Immunotherapy Different from Cluster Immunotherapy?

Comparison of traditional and cluster immunotherapy treatment schedules with allergy injections and calendar illustrations.

Traditional immunotherapy uses a gradual, steady schedule of one to two shots per week over approximately six months to reach your maintenance dose. Each appointment is short, usually followed by a 30-minute observation period to make sure your body responds well to the dose. It’s a proven, well-tolerated approach that has been the gold standard of allergy treatment for decades.

Cluster immunotherapy, by contrast, compresses that build-up phase into just six to eight weeks by giving multiple shots per visit. Traditional immunotherapy is the right fit for patients who prefer a slower, more spaced-out schedule, want shorter individual appointments, or aren’t in a rush to reach maintenance. At Juniper Allergy in San Antonio, Dr. Trott-Gregorio will help you decide which schedule fits your lifestyle and goals best.

Could Traditional Immunotherapy Be Right for You?

You want lasting allergy relief instead of another year of daily medications

You prefer shorter, more spaced-out appointments over intensive weekly visits

Your antihistamines, sprays, and eye drops have stopped giving you real relief

You have completed allergy testing and know your specific triggers

You can commit to weekly visits during the build-up phase and monthly visits after

You want to treat the root cause, not just manage symptoms

Our Team Of  Allergy Specialists

Hear It from Our Happy Patients!

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Jennifer Bailey
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It’s refreshing to see a doctor (and all of her staff) who show such compassion and caring for their patients. Highly recommended Dr. Trott!
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Sue Palitza
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I really enjoyed meeting Dr. Trott and her staff. Everyone was very nice and professional. Dr. Trott was very knowledgeable, listened to your concerns, and made you feel comfortable. When you leave, you feel comfortable that she can help you with any issues you are having. Excited to have her as one of my new doctors!
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Leslie Sebastian Sanchez
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My experience was Wonderful from the initial phone call to when I walked out the door . Dr. Trott listened to me and didn’t rush me along. She has such a calming presence and just made me feel like I was right where I needed to be . It was very thorough and not just a one size fits all place . The whole office staff was kind as well . If you are looking for an allergist /immunologist, look no farther than Juniper Allergy . I’m so happy I found Dr. Trott .
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William Griffenberg
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She is if not the best one of the best doctors I have ever met and I am old so I have seen a lot.
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Morgan Loudenslager
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Dr. Trott is worth the wait! She’s personable, doesn’t make you feel rushed and listens to your concerns. Very kind and helpful!
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A B
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This review has been a long time coming. Everyone here at Juniper has been literally amazing! That said, every.single.staff member at Juniper Allergy has been very welcoming since I transferred here. Honestly, out of all the doctors and medical facilities I have been a patient of (and I see quite a bit more doctors than your average person would), I could not think of a more welcoming place to be a patient other than Juniper Allergy. Edit: I do want to thank Dr. Trott for her advocacy of all her patients ... including myself here. She is one of the very few doctors who has shown exemplary compassion and empathy to provide the best service for her patients. I want to express that I would not be here today had I not received the type of care she has given me for my mast cell activation disorder. So to me she is the equivalent of a superhero. As cliche as that sounds, it is probably easier to just say that she is my lifesaver and I don't think I can name any other doctor with this type of regards. -Adam B.
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Evie Zambrana
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U simply LUV Juniper Allergy! When I first began attending, I thought it would be a miserable experience. Well, I was dead wrong! The employees were ALL so friendly, courteous, professional & extremely caring. They answer all my questions in a way that’s comprehensible. I consider my allergy injections “tender shots” that are improving my health. Thank you, Juniper!!

Why Choose Juniper Allergy For Traditional Immunotherapy

Board-Certified Allergist

Our board-certified Allergy and Immunology specialists deliver expert, evidence-based care focused on accurate diagnosis and effective, long-term treatment.

Over 13 Years of Trusted Care

For more than 13 years, Juniper Allergy has proudly provided comprehensive allergy and immunology services to patients and families throughout San Antonio.

Personalized Treatment

We create customized treatment plans based on your unique symptoms, medical history, and health goals to achieve the best possible outcomes.

Patient-Centered Care

Your comfort and wellbeing come first. We take the time to listen, answer your questions, and build lasting relationships so you always feel supported throughout your care.

Conditions Treated With Traditional Immunotherapy

allergy treatment

Allergic Rhinitis

Traditional immunotherapy reduces your immune system’s overreaction to pollen, dust, and mold, relieving chronic sneezing, congestion, and runny nose year-round.

Hand Eczema

Allergic Conjunctivitis 

We target the allergens causing your red, itchy, watery eyes with allergy shots, so you can finally stop rubbing them every day.

Asthma

Allergic Asthma

Allergy shots help desensitize your airways to allergy triggers, reducing asthma flare-ups and improving your breathing over the long term.

Stinging Insect Allergies

Stinging Insect Hypersensitivity

We build your tolerance to insect venom through traditional immunotherapy, significantly reducing your risk of a severe allergic reaction from future stings.

Start Feeling Better, Season After Season

Frequently Asked Questions

How many days between traditional allergy shots?

During the build-up phase, patients typically come in once or twice a week, with visits spaced anywhere from three to seven days apart depending on your treatment plan. Each appointment includes a single injection followed by a 30-minute monitoring period, and generally takes about 45 minutes in total.

How long does traditional immunotherapy take?

 The build-up phase runs for roughly six months with weekly or twice-weekly visits. Once you hit your maintenance dose, appointments space out to once every two to four weeks. The complete treatment course typically lasts three to five years, which is what’s needed to lock in lasting results that can continue for another five to fifteen years after your final dose.

What is the schedule for traditional immunotherapy?

During the build-up stage, you’ll visit once or twice a week for about six months, receiving one injection per visit. Once maintenance is reached, appointments shift to every two to four weeks. Sticking with the full three to five year treatment plan is essential to achieving long-term results.

Are allergy shots worth it?

If your allergies are getting in the way of daily life, work, or sleep, traditional immunotherapy is one of the most effective long-term treatments available today. Instead of masking symptoms the way antihistamines do, it goes after the root cause by gradually teaching your immune system to tolerate the allergens that trigger you.

How long does it take to start seeing results from immunotherapy?

Most patients notice meaningful improvement in their allergy symptoms within the first year of treatment. Some feel a difference even sooner, though the full benefits typically build over time as your immune system continues to adjust to the allergens introduced through each visit.

What is the best age for allergy immunotherapy?

Allergy shots are safe and effective for both children and adults. At Juniper Allergy, we care for patients of all ages and determine the right approach for you during your initial consultation. The best time to start is when allergies are noticeably affecting your quality of life and you’re ready to commit to the long-term treatment plan.