Can You Be Allergic To Mushrooms?

Mushrooms are celebrated for their savory flavor, nutritional benefits, and versatility in recipes—from risottos to wellness tonics. But for some, that same ingredient can lead to sneezing, skin rashes, or even life-threatening reactions.
It might sound surprising, but yes, you can be allergic to mushrooms, and the symptoms might already be affecting you without you realizing it.
Understanding Mushroom Allergy
A mushroom allergy occurs when the immune system sees the proteins or molds in mushrooms as harmful substances. This reaction can trigger symptoms ranging from mild irritation to severe respiratory distress. While not as common as allergies to peanuts or shellfish, mushroom allergies are real, and for some, they’re serious.
It’s also important to distinguish between a mushroom allergy and a mold allergy. While both involve fungi, they’re not always linked. A person allergic to mold may not necessarily react to mushrooms, and vice versa. However, some individuals are sensitive to both due to overlapping proteins.
Common Culprits
The most common mushrooms linked to allergic reactions include:
✔ White button mushrooms
✔ Shiitake
✔ Portobello
✔ Oyster mushrooms
Interestingly, reactions may not always come from eating mushrooms. Airborne spores from dried or uncooked mushrooms can also trigger symptoms, especially in more severe cases.
Mushroom Allergy Symptoms
Mild Symptoms
For many, symptoms begin subtly and can be mistaken for seasonal allergies or mild food intolerances:
✔ Sneezing
✔ Nasal congestion
✔ Itchy eyes
✔ Mild skin rashes or hives
✔ Gastrointestinal discomfort (such as bloating or nausea)
More Severe Reactions
In some cases, mushroom allergies can lead to more serious issues:
✔ Swelling of the lips, tongue, or throat
✔ Difficulty breathing
✔ Wheezing or chest tightness
✔ Anaphylaxis (a rare but life-threatening reaction requiring immediate treatment)
Who Is at Risk?
You may be more likely to develop a mushroom allergy if you:
✔ Have a family history of food allergies
✔ Are allergic to other fungi, molds, or yeasts
✔ Have been exposed to mushrooms frequently (e.g., chefs, food handlers)
Diagnosis: How to Know for Sure
If you suspect a mushroom allergy, speak with an allergist. Diagnosis typically involves:
✔ Skin prick tests: A small amount of mushroom extract is applied to your skin to observe for a reaction.
✔ Blood tests: These measure the presence of mushroom-specific IgE antibodies.
✔ Elimination diets: You remove mushrooms from your diet under medical supervision and slowly reintroduce them to test your tolerance.
Never self-diagnose or attempt a mushroom elimination diet without professional guidance, especially if you’ve had strong reactions in the past.
Treatment and Management of Mushroom Allergy
The good news is that mushroom allergies are manageable. Here’s how:
Avoid Mushrooms
It might sound obvious, but complete avoidance is often the most effective strategy. This includes:
✔ Fresh and cooked mushrooms
✔ Mushroom powders in supplements
✔ Mushroom-based broths and seasonings (often used in vegetarian or Asian cuisines)
Read Labels Carefully
Mushrooms can sneak into unexpected places. Always check ingredient lists on:
✔ Sauces
✔ Packaged soups
✔ Plant-based meat alternatives
✔ Health drinks or supplements (especially those with reishi, lion’s mane, or cordyceps)
Carry Medication
For those with a history of strong allergic reactions, an epinephrine auto-injector (like an EpiPen) may be prescribed by your doctor. Antihistamines can also help with milder reactions.
Communicate Your Allergy
When dining out or attending events, don’t hesitate to inform the chef or host about your allergy. Cross-contamination in the kitchen can pose a hidden risk, especially in dishes that use mushroom-based stock.
Prevention and Lifestyle Tips
Even if you only have mild symptoms, it’s important to stay proactive:
✔ Keep a food diary to track symptoms after meals.
✔ Ask for detailed ingredient information when ordering food.
✔ Join allergy support groups for community insights and up-to-date research.
✔ Keep your healthcare provider informed about any changes or escalations in your symptoms.
Keep Your Mushroom Allergies in Check

Mushroom allergies can feel like an unexpected inconvenience, especially if you enjoy plant-based eating, but they don’t have to control your life. With the right precautions, you can maintain a healthy, delicious diet that supports your lifestyle without triggering unpleasant symptoms.
If you’ve experienced symptoms after eating mushrooms or suspect you’re reacting to airborne spores, don’t wait. Talk to our allergists in San Antonio, get tested, and create a personalized plan to stay safe and symptom-free.